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Given a presumed single cell of origin for any individual malignancy, the basis for this functional heterogeneity has been explained by one of two models.
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In cross 3D1 × 3D7 nearly half of the total phenotypic variance was explained by one QTL on chromosome 11, whereas in cross 1A5 × 1E4 a similar amount of variance was explained by six QTL distributed across several chromosomes, suggesting a more complex genetic basis of melanin production in cross 1A5 × 1E4 compared with cross 3D1 × 3D7 (Table 5).
According to BioQuali, the observation on CDKN1C mRNA must be explained by one of these entries.
If a high proportion of variance is explained by one variable, then this variable has a strong effect on the outcome of interest.
It was explained by one interviewee that typing results had acted like a catalyst on the organisation: I just think, as I say I can't tell you what difference it can make.
Howard Metzenbaum, a former Democratic Senator from Ohio who is now the chairman of the Consumer Federation of America, said after today's hearing that the move by several senators to reach a quick compromise on the homestead provision and the overall bill was explained by one thing.
While the phenomenon may initially seem counter-intuitive, it may be explained by one of several underlying mechanisms, including a U-shaped dose response relationship for gene-on-trait, greater "fitness" in heterozygotes, or hidden stratification in one homozygote class.
Part of it, however, might be explained by one final theory of supernatural plausibility.
Medvedev's galloping lead can be explained by one thing: the Putin factor.
These results suggest that the positive relationship between cerebral volume and cortical folding across species cannot be explained by one set of selective pressures or genetic changes.
The programme – an hour-long talk show – presented a paradox that could only be explained by one of Einstein's equations about the time-space continuum.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com