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Furthermore, the implications of withholding antibiotic therapy in children with bulging eardrums have not previously been evaluated in high quality studies.
Although the impact of those tests have been evaluated in high income countries, their use could be highly relevant in poorer countries with a higher tetanus incidence due to a lack of tetanus immunity in wounded patients.
This reduction was apparent for ceramic filters, biosand systems and LifeStraw® filters, but plumbed in filtration has only been evaluated in high- income settings and a statistically significant effect has not been demonstrated.
The EULAR recommendation to provide joint protection and hand exercises for all patients with hand OA is based largely on expert opinion and has not been evaluated in high quality randomised controlled trials.
Trastuzumab has been evaluated in high HER2 expressing ovarian cancer and in this group, while only 7.5% of patients showed a response, 39% demonstrated stable disease (Bookman et al, 2003).
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Fetal arousal tests such as vibroacoustic stimulation have largely been evaluated in high-income countries.
Plumbed-in filtration has only been evaluated in high-income settings (USA).
Plumbed-in filtration has only been evaluated in high-income settings (low quality evidence).
However, the potential preventive effect of dopamine has not been evaluated in high-risk cardiovascular surgery.
Plumbed in filters have only been evaluated in high-income settings (RR 0.81, 95% CI 0.71 to 0.94, three trials, 1056 participants, fixed effects model).
7 11 Complications during pregnancy and birth at an advanced maternal age (either defined as 35 years and older or 40 years or older) have also been evaluated in high-income countries.
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