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The performance of multiple myeloma (MM) therapies in a general patient population and specific eligibility criteria that might limit enrollment into randomized controlled trials (RCTs) have not been evaluated in depth.
Nutmeg and Clove have not been evaluated in depth for their pharmacological properties, inspite of their traditional use in numerous medical conditions.
What has not yet been evaluated in depth is the ability many of the available PAR1 antagonists to act as either full or biased antagonists for either PAR1 or PAR2 activation.
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After ranking them by the weighted sum, the top 5% plans were evaluated in-depth by simulation model.
All scores and calculations are available as a spreadsheet file in Additional file 2. The software packages that were evaluated in-depth after the preselection step are described in the following.
Combined with the results from this study where low levels of HDAC4 correlated with drug resistance, it is important that the mechanistic involvement of HDACs in EMT, CSCs and drug resistance be evaluated in-depth before their selective targeting in clinics.
For pandemic preparedness, antiviral drugs and vaccine candidates against airborne-transmissible virus should be evaluated in depth.
The sulfinyl precursor route for the synthesis of poly p-phenylene vinylene) (poly p-phenyleneia an anionic polymerization procedure employing dedicated initiators is evinylene in dePPV.
During their studies, in which only the first two controller types were evaluated in depth, glucose was kept within the euglycemic range on average 71% of the time, showing the potential and benefits of such automated closed-loop systems.
LD therefore has to be evaluated in depth to determine whether the tagging of the genome is sufficient for GWAS purposes.
This information needs to be evaluated in depth because alcohol gel handrubs for quick hand hygiene were available in the majority of hospitals (73%) where participants were working; WHO Guidelines recommend routine use of alcohol-based handrubs as the gold standard in health care worldwide (after initial hand washing) [ 21].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com