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It has been established that higher rates of congenital malformations occur in areas of higher natural radioactivity.
It has been established that higher TYMP (as well as lower DPYD) expression in tumors resulted in higher intratumoral concentrations of 5-FU, as well as a more potent antitumor effect of capecitabine [ 42– 42].
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As the clays receive increasing amounts of acid, it has been established that high amounts of Pb can be retained if the buffer capacity prevents the pH from dropping to values where precipitation mechanisms are not operative.
Moreover, it has been established that high insoluble glucan content in the EPS matrix acts as a diffusion barrier, trapping acid near the tooth surface and thereby increasing the extent of the acidification period [41], [42] and the cariogenicity of human plaque [43].
Furthermore, it has been established that high cattle density is a risk factor for human VTEC O157 H7 infection [ 14].
It has been established that high levels of blood glucose could lead to the development of complications in DM via posing oxidative stress, protein kinase C activation, and the accumulation of AGEs [ 10– 13].
It is established that higher APACHE II scores and longer length of ICU stay are associated with higher risk of ICU readmission [ 3].
From SARs it is established that high pore volume to surface area ratio, high metal dispersion, high reducibility and high support basicity are the essential traits of an active and stable catalyst.
Moreover it was established that high quality copper coatings on tantalum and titanium electrodes could be formed only within the potential range Ec = −(1.8 2.0) V (vs. Pt), which corresponded to the rising branch of the second current peak on the cathodic polarization curve.
The mechanism of hypertension-induced renal fibrosis is not well understood, although it is established that high levels of angiotensin II contribute to the effect.
Acceptable daily intakes can be established that are higher than the default TTC for many structural classes (e.g., mono-functional alkyl halides and certain aromatic amines).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com