Sentence examples for been established that activated from inspiring English sources

Recently it has been established that activated CD74 acts as a signaling molecule by nuclear activation of NF-κβ [ 46].

Over the past years it has been established that activating and inhibiting MHC-specific receptors regulate the activity of NK cells.

It has been established that the hormone activates MAPKs (ERK1/2) and Akt.

Although it has been established that DMXAA can activate macrophages through a number of key inflammatory pathways including the NF- κB (Ching et al, 1999), type 1 interferon (Roberts et al, 2007), NOD2 (Cheng et al, 2010), and MAP kinase (Sun et al, 2011) pathways, the DMXAA 'receptor' had not been identified.

It has been established that the alkaloids activate sodium channels and excite cardiac, neural and muscular tissues above normal levels.

Since it has already been established that Gi-coupled receptors can activate AC2, although in the presence of activated Gsα [ 32, 45], we wished to compare the actions of Gβγ released from Gq-coupled muscarinic receptor to those of Gβγ liberated by SST receptor activation.

While it has long been established that human vascular endothelium can activate alloreactive CD8 T cell in vitro [35] very few studies have examined in detail the response of alloreactive CD8 T cells toward endothelial cells.

For example, it has been established that enhancers of a gene more strongly activate transcription of the paired copy in trans if the cis core promoter is weakened or removed (Martínez-Laborda et al. 1992; Morris et al. 1999, 2004; Lee and Wu 2006; Gohl et al. 2008).

Once it has been established that the participant has consented to feedback, the next stage of the pathway is activated.

It is established that Phospholipase D (PLD) activates mTOR signaling, through the binding of its product phosphatidic acid (PA) to mTOR protein.

It has been widely established that activated p53 is involved in growth arrest, DNA repair, apoptosis, and senescence pathways.