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Exact(38)
Individual characteristics may influence the kinetic parameters (pharmacogenetics): in the case of hydralazine, fast or slow metabolism is genetically determined, and in some studies, doses have been escalated or de-escalated according to individual metabolic parameters [ 57– 57].
For the 264 patients who had their doses escalated to >30 mg/kg per d, overall median transfusional iron intake was 0·34 mg/kg per d for the 6 months preceding dose escalation, which remained constant once doses had been escalated.
Although it remains unclear whether the PCT protocol could not identify the correct patients in whom therapy should have been escalated or whether the intervention was not beneficial per se, therapy escalation based on PCT concentrations cannot yet be recommended in the sepsis setting [ 26].
We are disturbed that the issue has been escalated".
The war of nerves against China has been escalated.
Davutoglu added that the crisis in Syria has been escalated by Russia's involvement in air strikes.
Similar(22)
And the attacks have been escalating.
And their violence and brutality has only been escalating.
But pressure on the office has been escalating.
Violence has been escalating in Tunisia over the past two years.
These concerns have been escalating for years.
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