Sentence examples for been engineered to encode from inspiring English sources

To introduce bioreactivity into live systems, the genetic code has recently been engineered to encode a new class of Uaas, the bioreactive Uaas.

A strain whose chromosome had been engineered to encode a lac repressor GFP (green fluorescent protein) fusion was used as a host for a low copy number plasmid that carries an array of five lac operator sites.

To this end, IAV, lacking a functional NS1 antagonist, was engineered to encode individual siRNAs against antiviral host genes in an effort to rescue attenuation.

Murine moloney virus and serotype 9 of adeno-associated virus were engineered to encode improved Cre recombinase for genetic deletion in miR-21fl/fl mice.

To exmine the feasibility of virus-encoded mimic epitopes to initiate CNS autoimmunity, we recently developed a molecular mimicry model of virus-induced demyelinating disease wherein a non-pathogenic variant strain of TMEV was engineered to encode a 30-mer peptide encompassing the immunodominant myelin proteolipid protein, PLP139 151, epitope.

For equal expression, all constructs had the same length of Foxp3 cDNA but were engineered to encode different Foxp3 forms.

Significantly, when this transgene is engineered to encode the woodchuck post transcriptional element that results in forced localization of the mutant RNA to the cytoplasm, the toxicity associated with these RNAs disappears, and they are no longer capable of dysregulating normal myoblast differentiation [27].

The DNA vaccine was engineered to encode a chimeric human-rat HER2 protein and was coupled to in vivo electroporation.

Synthesised mRNA can be engineered to encode multiple types of transcripts, including synthetic poly-epitopic nucleotide sequences, and has a favourable safety profile (Kuhn et al, 2011).

A recombinant baculovirus was engineered to encode residues 956 1256 of IGF1R with the substitution C1207S using the pFastBacHT B plasmid (Life Technologies, Carlsbad, California).

Lastly, prior to introduction into patients, these bacterial strains will need to be engineered to encode "kill switches" or modifications that prevent the propagation or release of protein delivery strains in the environment.