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Here, we highlight soft material systems that have been engineered to display programmable buckles and creases.
In this work, the Bacillus licheniformis β-lactamase BlaP has been engineered to display heterologous polypeptides in a permissive and solvent-exposed loop.
A virus-like particle (VLP) has been engineered to display Pfs25 on its surface; the coat protein (CP) of Alfalfa mosaic virus was fused to Pfs25 and expressed in Nicotiana benthamiana.
To determine if plants can be used to produce CVPs able to activate peptide-specific major histocompatibility complex (MHC) class I-restricted CD8+ T cells, potato virus X (PVX) has been engineered to display the H-2Db-restricted epitope ASNENMETM of influenza A virus nucleoprotein (NP).
The icosahedral protein scaffold (1.5 MDa) generated by self-assembly of the catalytic domains of the dihydrolipoyl acetyltransferase core of the pyruvate dehydrogenase multienzyme complex from Bacillus stearothermophilus has been engineered to display 60 copies of one or more peptide epitopes on a single molecule (E2DISP).
Immunization with stabilized trimeric gp120, with gp120 conformationally altered by sCD4 to expose buried epitopes, by decreased glycosylation, or with gp120 that has been engineered to display conserved epitopes often have been immunogenic, but with few exceptions all have failed to elicit Abs that are broadly neutralizing [40], [41], [42], [43], [44].
Similar(52)
The resulting antenna (inverted taper+directors, Figure 3a) can be engineered to display directivity values between 5 and 150, providing an extremely high design flexibility.
CPMV was engineered to display a 25 amino acid peptide derived from the Bacillus anthracis protective antigen on the surface loop of the large coat protein subunit.
In this work, a modular murine polyomavirus (MuPyV) virus-like particle (VLP) was engineered to display a GAS antigenic peptide, J8i.
Adenovirus particles can be engineered to display exogenous peptides on their surfaces by modification of viral capsid proteins, and particles that display pathogen-derived peptides can induce protective immunity.
In order to further improve this form of treatment, L. rhamnosus GG was engineered to display surface expressed IgG-binding domains of protein G (GB1, GB2, and GB3) which capture HBC-derived IgG antibodies (HBC-IgG) and thus target rotavirus.
More suggestions(17)
been engineered to express
been investigated to display
been engineered to replace
been known to display
been engineered to satisfy
been ordered to display
been used to display
been engineered to have
been engineered to celebrate
been upgraded to display
been identified to display
been engineered to fly
been urged to display
been engineered to pass
been engineered to blend
been engineered to suffer
been engineered to provoke
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com