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In particular, the RNA-guided CRISPR/Cas9 system has recently been engineered to create site-specific double-strand breaks for genome editing or to direct targeted transcriptional regulation.
In addition, hybrid promoters have been engineered to create different types of logic gates and layered to generate complex circuits.
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Zinc finger nucleases can be engineered to create highly efficient and precise changes to the genetic information within living cells.
Furthermore, a triple mutant of BspQI (Nb.BspQI, N235A/K331A/R428A) was engineered to create a bottom-strand nicking enzyme.
A nucleic acid-based (NABTM) scaffold can be engineered to create functional group and topological diversity in a library.
Moreover, supply chains for biomass are still being developed, so the availability of feedstock will change.Research is continuing into using other micro-organisms, such as yeast, which might be engineered to create similar metabolic pathways.
First, because the antisense RNA mechanism relies on RNA-RNA interactions, we show how the specificity of the natural system can be engineered to create variants that independently regulate multiple targets in the same cell.
However, owing to a diversity of available pathway precursors along with natural and engineered enzyme 'parts', microbial cell factories can be engineered to create alternative, renewable routes to many of the same aromatic products.
Due to the heavy presence of the state in the Chinese stock market, some onlookers surmised that the stock market crash was engineered to create a financial coup d'état.
The Spurs new offense is engineered to create lots of high-efficiency layups and corner three-pointers.
Smolke said the purpose of producing hydrocodone was to show that yeast can be engineered to create a compound that a plant doesn't have the cellular machinery to produce.
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