Sentence examples for been engineered to bind from inspiring English sources

It has been engineered to bind highly to penicillin binding protein 2a (PBP2a).

When introduced into an Fc fragment that had been engineered to bind to Her2/neu via a novel antigen binding site located at the C-terminus of the CH3 domain, the novel inter- and intra-domain bonds also brought about a significant increase in thermostability.

PUM-HD domains have also been engineered to bind to cytosine (which is not observed in any of the natural PUF binding specificities) and to bind targets longer than 8 bases by increasing the number of repeats [ 32, 33].

For that reason, and the lack of alternative therapies, America's Food and Drug Administration has recently agreed to expedite the review process for these two potential treatments.Unlike most antibodies, MEDI3902 is bi-specific meaning it has bi-specific meaningbitd to two different targets.

This domain consists of a 5 kDa protein that has been engineered to bind HSA with high affinity and is designed to enhance the efficacy of biopharmaceuticals by extending their circulatory half-life in patients.

A protein without natural binding functions was engineered to bind HIV-1 integrase.

The DARPin MP0112 was engineered to bind VEGF-A with a K d of 1 4 pmol/L (Souied et al., 2014b).

The avimer C326 (AMG220), consisting of three A-domains, was engineered to bind IL-6 with picomolar affinity (Silverman et al., 2005).

Based on these findings, Caf1M was engineered to bind Caf1 faster, tighter, or both faster and tighter.

Our results also demonstrate that peptides can be engineered to bind to specific faces of COM crystals.

The active site of the Tetrahymena ribozyme was engineered to bind an oligonucleotide derived from the 3' end of N-formyl-methionyl-tRNA fMet).