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Traditionally, bone grafting procedures and segmental bone transport have been employed for bone tissue regeneration.
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Autogenous iliac bone graft, in general, has been employed for closing the bone defect at the alveolar cleft.
It has been employed for visualisation of bone and joint infections, while Ga was successfully applied in tumor imaging [ 10].
Further, enzymatically degradable hydrogels have been employed for wound healing and bone regeneration.
Various methods, such as allografting [ 1, 2], pasteurized autografting [ 3], and bone elongation [ 4], have recently been employed for the reconstruction of limbs affected by malignant bone tumors.
Many animal models have been employed for intra- and extraoral healing of bone around metal implants, including well-established models of bone healing using sheep [ 14].
Various piezoelectric materials have been employed for different tissue repair applications, particularly in bone repair, where charges induced by mechanical stress can enhance bone formation; and in neural tissue engineering, in which electric pulses can stimulate neurite directional outgrowth to fill gaps in nervous tissue injuries.
Tide mills have been employed for centuries.
Weighted subtraction imaging was employed for material and bone separation.
While there are many polymeric materials that may be employed for the regeneration of bone and cartilage tissue, we will focus specifically on those that have been more extensively applied, showing promising outcomes.
The TCP-gradient PCL fibrous matrix can potentially be employed for the biomedical application to the bone and bone-to-tendon regeneration.
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