Sentence examples for been eliminated during evolution from inspiring English sources
Thus, the Phe441 mutation could have been eliminated during evolution.
We found that both PE_PGRS17 and PE_PGRS18 are under purifying selection as the majority of disadvantageous phenotypic changes would have been eliminated during evolution.
Among these retrocopies, retrogenes were more prevalent in old than young retrocopies, which indicates that most retrocopies may have been eliminated during evolution, even though some retrocopies survived, attained biological function as retrogenes, and became old.
The overrepresentation of the retrogenes among the old retrocopies and decrease in frequency of relatively old retrocopies indicated that many of the retrocopies might have been eliminated during evolution, which was consistent with our predictions based on the expected lack of regulatory elements and introns in the retrocopies.
To address variations in functional significance, a transition between the following two coexisting classes was postulated for the proteins: the class of optional proteins that are essential for ecological adaptations, which naturally emerge and are eliminated during evolution, and the class of proteins essential for basic life processes, which are protected from immediate loss.
Many retrocopies may have been eliminated during coelacanth genome evolution because of disrupted genetic structure defects.
But such inherited mutations are hard to find, because they're usually eliminated during evolution, he explains.
As H3K27me3 represents a repressive mechanism for controlling the expression of genes [ 24, 36, 37], it is likely that Alu insertions into vicinities of these genes are selectively eliminated during evolution to ensure gene function in development.
Based on the obtained results, we suggest that retrocopies attained biological relevance and were subject to natural selection following fusion with existing genes or acquisition of new gene elements, although many retrocopies have ultimately been eliminated from the genome during coelacanth evolution.
This suggests that any point mutations that might have rendered self-binding to be of lower affinities were either suppressed or eliminated during evolution.
