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Studies on the circadian variation of large portions of the genome have been done in bone marrow derived mesenchymal cells and osteoblasts [9] [11] leading to the proposal that clock genes may be involved in complex processes like bone formation [12].
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However, most of the studies showing Akt activation in response to RANKL have been done in in vitro models of bone marrow co-cultures or using murine cell line, RAW264.7 cells.
Additionally, computed tomography (CT) imaging was done in cases of marked bone destruction.
For closure of bone gap, acute docking and distraction was done in 18 cases and segmental bone transport in 22 cases.
"It seems that this was done in order to throw a bone to the United States president," Avi Roeh, the chairman of the local settler council, told Israel Radio.
The preparation of the bone was done in the usual manner as is done when cutting with an oscillating saw.
Standard laboratory tests were done in order to detect metabolic bone disorders and vitamin D insufficiency, as described previously (Mäkinen et al. 2007).
Work phases were separated into two rooms: Sample preparation ("dirty work" e.g. cleaning, drilling and crushing of bones) was done in one room in a laminar flow hood equipped with extra suction fan and UV-light.
In our series of 30 patients, primary bone grafting was done in only 3 patients.
There was nonunion in one patient in the PTP group; bone grafting was done in that case, which eventually led to fracture healing.
A study characterizing the microvascular bed in the bone marrow was done in adult dogs after perfusion of gelatin containing india ink.
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