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More than 30 autophagy-related proteins (Atg) have been discovered to regulate autophagy.
This complexity is further increased because miRNAs have been discovered to regulate gene expression at the transcriptional level [ 16].
A number of important oncogenic and tumor suppressor miRNAs have been discovered to regulate important genes and pathways such as p53 and IL6-JAK-STAT signaling.
Similar(57)
Recently, a new cast of players was discovered to regulate the Golgi and ERGIC: four unrelated cytoplasmic phospholipase A (PLA) enzymes, cPLA2α (GIVA cPLA2), PAFAH Ib (GVIII PLA2), iPLA2-β (GVIA-2 iPLand and iPLA1γ.
miRNAs were discovered to regulate other ear-related human clinical features.
MiR-138 was discovered to regulate CFTR expression through its interaction with the transcriptional regulatory protein SIN3A.
Two Arabidopsis bHLH transcription factors, that is, ICE1 and ICE2, were discovered to regulate the transcription of CBF3 and CBF1, respectively, under cold stress.
One such example of a motogen is Hepatocyte Growth Factor (HGF), which was discovered to regulate the migratory abilities of subpallial-derived cortical interneurons.
During the past decades, the functions of these GPCRs have been discovered to not only regulate leukocyte trafficking and promote immune responses, but also play important roles in homeostasis, development, angiogenesis, and tumor progression.
Although bacterial riboswitches are widespread and characterized, only a single eukaryotic, thiamin-pyrophosphate-binding riboswitch has recently been discovered to direct gene expression by regulating mRNA splicing in fungi, green algae and land plants.
Protein S-nitrosylation which is covalently modified by NO has recently been discovered to play important roles in regulating diverse pathways [ 5– 7] and other biological activities [ 8], such as chromatin remodeling [ 9], transcriptional regulation [ 10], cellular trafficking [ 11], and apoptosis [ 12].
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