Sentence examples for been directed to improving from inspiring English sources

Substantial efforts have been directed to improving the FokI architecture to limit off-target cleavage, including the design of obligate heterodimeric pairs (Ramalingam et al. 2011; Szczepek et al. 2007), and the use of longer DNA-binding modules (Shimizu et al. 2011), such as TALEs (Christian et al. 2010).

Thus, during the last decades efforts have been directed to improve nutrient management practices and breeding for crop varieties with high nitrogen use efficiency (NUE) [ 4– 6].

Recently, several initiatives have been directed to improve consistency, relevance and fidelity in the process of transforming clinical data into administrative datasets and subsequent practice-changing results.

Treatment of pressure ulcers is directed to improving host factors and providing an optimum wound environment.

Governance related issues should assure that health investments are directed to improving health standard of the population.

For possibly cost-effective technologies very sensitive to the policy routes (e.g. CSP and marine), R&D efforts should be directed to improving their techno-economic performance.

[ 14- 16] Since results are available on most patients tested by IGRA, program resources may be directed to improving follow-up of patients with positive IGRA results.

Immediate attention needs to be directed to improving usage and adherence rates [ 21], and new methods need to be explored which cater for young men's mental health needs and expectations [ 22].

It should also be stressed that clinical and research efforts be directed to improving treatments and to examining their effectiveness for this patient population at extremely high risk of suicide.

Although emerging HIT applications are directed to improving the quality of care and economies of service [ 1], some investigators have warned that the use of HIT may threaten the very nature of the patient-provider relationship by undermining trust, inhibiting disclosure of relevant concerns, and by hampering meaningful discussions of patient preferences that impact treatment decisions [ 2- 5].

With few exceptions, for many British Idealists, philosophy is integrally related to practical life and should be directed to improve the condition of societyr.