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Urothelial carcinoma of the bladder is a common malignancy which has historically been difficult to treat in its advanced stages.
Cachexia has been difficult to treat, and the most promising new therapies inhibiting ActRIIB ligands, such as myostatin, a protein that promotes muscle breakdown, have been pulled after clinical trials indicated safety issues.
He continued, saying "after seeing a large number of spill-related patients and treating their less serious problems, I found myself with a potpourri of what appear to be neuroendocrine disorders that have been difficult to treat".
Large-area cartilage defect has been difficult to treat in orthopedics for years.
Conference participants agree that prevention is critical for children, families, communities, and workplaces because obesity has been difficult to treat thus far.
Events occurring slower than the time scale of the barrier crossing of the actual chemical event have been difficult to treat and characterize.
Similar(50)
Drug-resistant infections are difficult to treat, and sometimes fatal.
Fungal infections of the nail can be difficult to treat.
It is difficult to treat as it's chronic, but so are eczema and diabetes.
It is difficult to treat this work as illusion, even a theatrical illusion.
The pain of PHN, which is difficult to treat, has been described as burning, throbbing, aching, stabbing or shooting.
More suggestions(18)
been difficult to process
been difficult to handle
been difficult to cure
been difficult to accommodate
been difficult to put
been difficult to pick
been careful to treat
been difficult to prove
been difficult to communicate
been difficult to persevere
been difficult to work
been difficult to account
been difficult to prettify
been difficult to endure
been difficult to confirm
been difficult to write
been difficult to find
been difficult to wake
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com