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Polo-like kinase 1 (Plk1) is an essential kinase that regulates spindle assembly, mitotic entry and chromosome segregation, but because of its many mitotic roles it has been difficult to specifically study its post-anaphase functions.
As such, it has been difficult to specifically target the contribution of relational knowledge of the hierarchy to transitive inferences, over mechanisms based on retrieval-mediated associative linking (Kumaran and McClelland, 2012 and the use of elemental values (Fersen et al., 1991; Frank et al., 2003).
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Furthermore, all these parameters are interrelated and it is difficult to specifically extract the relevant one.
It can be difficult to specifically pinpoint the cause of such discrepancies in studies using a range of real-world object categories.
Without a comprehensive set of water samples from all parts of the water course (650 km mainstem, >1200 km of tributaries), it is difficult to specifically pinpoint where fish might have moved to experience correspondingly high dissolved 87Sr/86Sr ratios.
Although it is difficult to specifically test these hypotheses, information on the ecological and genetic correlates of variation in venom composition within species will enhance our understanding of the forces driving Conus venom evolution.
Thus, similarly to the case of purine and pyrimidine biosynthesis pathways, genes involved in amino acid biosynthesis appear to share phyletic vectors to such an extent that it is difficult to specifically distinguish individual amino acid biosynthesis pathways by comparing phyletic vectors alone.
It is difficult to specifically attribute the instrument stand to an individual Mayo.
It can thus be difficult to specifically link observed cellular responses to inhibition of the desired target protein.
Multiple grants may be used to fund many different studies, so it is difficult to specifically determine the funds used to support a given article.
Because the depth of coverage across the genome was different between lines, it was difficult to specifically determine whether the SNPs are unique to any particular genotype.
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CEO of Professional Science Editing for Scientists @ prosciediting.com