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Exact(7)
"This will propel a step-change in knowledge and technology, which will facilitate exploration by private companies in areas that have historically been difficult to explore".
There is one issue that is missing here, though it would have been difficult to explore it without considerably more explanation (and perhaps other manuscripts).
In particular, the growth laws under dynamically changing environments have been difficult to explore, because of the rapidly changing conditions.
The associations between BMI and height with thyroid cancer have been difficult to explore in previous small studies owing to the low incidence of this disease.
The contribution of individual amino acids within transmembrane helices to GPCR dimerization has, however, been difficult to explore or to generalize.
In terms of the cardiovascular system, the effects of bedding systems have been difficult to explore, and there are very few quantitative analyses available.
Similar(53)
There are many places that we don't know because it's difficult to explore".
The area is still closed to non-nationals, so it's difficult to explore, and there are no roads.
Hearing about his bad boy youth, one is struck by how similar it is to his bad boy adulthood, although it is difficult to explore this theory.
It can be difficult to explore toxic love in contemporary novels: you are reflecting the true nature and experience of being with – or sometimes, being – a troubled person.
Usually the pancreas is difficult to explore due to the interposed intestinal bloating.
More suggestions(19)
been difficult to gauge
been difficult to evaluate
been difficult to navigate
been difficult to survey
been difficult to establish
been difficult to discover
been difficult to identify
been difficult to pin
been difficult to prove
been difficult to elucidate
been difficult to communicate
been difficult to concentrate
been difficult to persevere
been difficult to measure
been difficult to test
been difficult to transform
been difficult to perform
been difficult to define
been difficult to classify
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com