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It has therefore been difficult to discover the genes that contribute to blood pressure variation using traditional approaches including candidate gene studies and linkage studies.
For example, functional genomics studies of the pine engraver beetle, Ips pini (Coleoptera, Scolytidae) [ 10- 12], assisted the identification of important pheromone-biosynthetic genes that otherwise would have been difficult to discover [ 13- 15] and led to subsequent understanding of their regulation and biochemical roles [[ 13, 16, 17], Figueroa Teran et al., unpublished].
Moreover, it has been difficult to discover whether HLA-Cw6 itself is associated with PsA, because this is the primary marker for psoriasis and most patients with PsA have cutaneous psoriasis; in contrast, some recent investigations have shown that both conditions share a 100-kilobase susceptibility region telomeric to HLA-C [ 6].
Similar(57)
He thinks those old matches were worthy of being adored as they were difficult to discover.
Dr. Landis explained that drugs were difficult to discover and expensive to research.
It is difficult to discover any point in calling talk "rabbit and pork".
The evolutionary reasons for reproductive success are difficult to discover in a society that uses modern birth control methods.
App stores are starting to resemble overstuffed stacks at a library — there's plenty of good material, but unless you know exactly what you're looking for, it can be difficult to discover anything new.
If it's a colleague, it shouldn't be difficult to discover, and if someone is emailing from outside the organisation; well, there's Google (other search engines are available).
In real estate, residences with a sordid past are referred to as "stigmatized properties" and it can be difficult to discover if a house falls into this category, since neither the seller, nor the seller's real estate agent, may be under any obligation to disclose that information.
GFD invasion is a type of gas cut that is difficult to discover and is not widely known.
More suggestions(16)
been difficult to learn
been difficult to uncover
been difficult to find out
are hard to discover
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been difficult to prove
been difficult to elucidate
been difficult to ascertain
been difficult to diagnose
been difficult to know
been difficult to understand
been difficult to distinguish
been difficult to discern
been difficult to recover
been difficult to detect
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com