It is difficult to create new diagrams of communication that elegantly and adequately express the full communication process, incorporating multiple facets of the signal, multiple channels, multiple interactants, dynamic factors, and effects of the environment, without becoming so complex as to lose visual effectiveness.
Reviewer 2 has pointed out that Figure 4 is somewhat confusing, in that it is difficult to tell from the diagram that TNF- α degrades the extracellular matrix (ECM).
The third important structural model, the random close-packing model for metallic glasses, is difficult to illustrate with a simple diagram.
After all, it's difficult to look at the following diagram and say to yourself, pulling your goatee, "Yes… yes, that should work just fine".
"The diagram is difficult to understand and has to be explained to be useful".
In particular, the passage of time may be difficult to convey in traditional tree diagrams.
As seen below, parts of the data are described inadequately; there are missing statistics, and the connectivity diagrams are difficult to follow.
We paid careful attention to the representation of population risks and benefits of screening (see web extra appendix 1) following our qualitative research with low literacy groups, which indicated that population diagrams were difficult to understand.
A benefit of internet-based resources, highlighted by parents and clinicians, is that they could include short video clips showing signs and symptoms, presenting information that is difficult to explain verbally or in diagrams.
They also require more skilled staff numbers and time and may be more likely to lead to mistakes in claims submission by providers as well as auditing by the purchaser that lead to denial of claims.Causal loop diagrams are difficult to follow for those who have not been involved in the details of constructing them.
