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It has been difficult to create effective vaccines for this serogroup in order to modify or reduce its morbidity.
It has traditionally been difficult to create full-thickness defects in the mandibles of rodent animals because of dissimilar anatomic structures with humans, interference from teeth of jaws, and limited surgical access.
"It's been difficult to create simulations where you could control optic flow and heading information".
It has been difficult to create nutrient deficiency in zebrafish because they eat plankton and baby shrimp, which are rich in various nutrients.
Similar(56)
It's difficult to create something.
It is difficult to create a new style, very difficult.
"A sense of urgency is difficult to create," he said.
The former is challenging to preserve, and the latter is difficult to create.
Bread, particularly the soft crumb inside, was difficult to create because it is so familiar.
Without this initial "friendly" interaction, group cohesion will be difficult to create.
Optimized models of complex physical systems are difficult to create and time consuming to optimize.
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