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Recovering 3-D motion of the object from the motion field has been difficult owing to the nonlinear system of equations involved, and the sensitivity of the system to noise.
This helped the chloroform to volatilise, which otherwise would have been difficult owing to the cold".
Addressing this issue has been difficult owing to the interconnectivity and complexity of brain-cell populations.
Thus, reliable quantification of the membrane transport of nonionic molecules has been difficult owing to the small amount of substrate transported.
The assessment of lymphatic characteristics in malignant tumours has historically been difficult owing to the lack of availability of lymphatic-specific markers.
Matrix metalloproteinases (MMPs) have an important role in ECM degradation, although attributing a specific role for individual MMPs has been difficult owing to functional overlap with other proteases.
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Walking is difficult, owing to the wide swath of bumpy plowed-in earth, not to mention the deep trench filled with water and still more barbed wire.
Scientific study of owls is difficult owing to their silent nighttime activity, with the result that the ecology, behaviour, and taxonomy of many species remain poorly understood.
Drawing a picture of the health of Noongar language is difficult owing to the ambiguities of what qualifies "speaking a language", Hanson says – when it means anything from "half a dozen words to speaking fluently" you could say almost all Noongar people speak their language.
Blinding of participants and researchers tends to be difficult owing to the nature of interventions.
However, estimation of pre-eruptive H2O content on arc magmas is difficult owing to degassing from erupting magmas.
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