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Human cord blood non-hematopoietic stem cells have been differentiated into multiple cell types such as endothelial cells, neurons, smooth muscle cells, adipocytes, chondroblasts and osteoblasts [ 12, 13, 15- 23].
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Furthermore, stem cell genes such as oct4, nanog, c-myc, pax3 and sox2 are significantly upregulated in rhabdospheres which can be differentiated into multiple lineages such as adipocytes, myocytes and neuronal cells.
MSCs isolated from Wharton's jelly are capable of being differentiated into multiple mesodermal cell types, including skeletal muscle and neurons [ 55– 57], and therefore may be valuable for repairing the peripheral nervous system.
3T3-L1 cells were differentiated into adipocytes in culture.
RICs were differentiated into hepatocytes as previously escribed54.
The latter was differentiated into static and dynamic subtypes.
Gametes are haploid, and may be differentiated into egg and sperm.
These stem cells were differentiated into retinal pigment epithelium cell before analysis.
With K = 3, subsp. fastigiata was differentiated into two groups, corresponding to var.
Ff-hiPSCs were differentiated into blood cells as described previously30 with some key modifications.
Ff-hiPSCs were differentiated into insulin-producing cells as described previously21.
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