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In the experiment reported here, the cells have been differentiated for more than 150 days before the transplantation so that the difference in differentiation time between mouse and human has already been accommodated.
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Briefly, cells were differentiated for more than 48 h, and then ESA was added to cells.
In only a few studies, cells were differentiated for more than 20 30 days and data on stability of gene expression or metabolic function after prolonged culture were only occasionally reported.
Because pre- and post-transfusion screening and monitoring payments could not be differentiated for patients with more than 1 transfusion claim within an episode, we combined screening and monitoring payments 3 days prior to and 3 days post transfusion episode.
hNPCs were differentiated for 24 h.
N2 cells were differentiated for 6 days.
Similarly, miR-206-KO BMDMs were differentiated for 10 days which also yields terminally differentiated macrophages.
MAP2+ neurons and GFAP+ glia could be detected after differentiated for more than 35 days.
An alternative, neutralist, explanation for the overrepresentation of GO terms among differentiated loci is that genes differ in polymorphism rates, and genes with more polymorphism are more likely to have some polymorphisms which are differentiated due to stochastic forces.
The bill changing how student fees are distributed does not explain how groups that embark on more expensive ventures -- like building a solar car, for instance -- would be differentiated from, say, an a capella group or a cheese appreciation club.
A more proximal and a distal part can be differentiated.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com