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RAREVATOR is a Perl script that executes the UnifiedGenotyper module of GATK for genotyping all the SNVs and InDels that belong to RRA loci and a series of R scripts that have been devised to filter and annotate the resulting variants.
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Various solutions have been devised to overcome the aforementioned limitations.
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A convex optimization approach in terms of linear matrix inequalities, and which incorporates information on available bounds on the parameters variation, is devised to the filter design based on Lyapunov functions with rational dependence on the system parameters.
With the help of a nominal system, an online estimator with gradient adaption law and low-pass filter is devised to evaluate output uncertainty.
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Governors were devised to prevent this.
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