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For moderate-to-severe psoriasis, effective biologic therapies have been developed to block specific cytokines (e.g., etanercept) or interfere with T-cell activation (e.g., efalizumab).
Several chemicals, such as Nutlin and MI-219, have been developed to block the interaction between Mdm2 and p53 (Shangary et al., 2008; Vassilev et al., 2004).
Many types of inhibitors (i.e. antibodies, peptides, small molecules) have been developed to block ICAM-1/LFA-1 interandionsomend sofe of these molecules have reached clinical trials.
Recently, a variety of tissue engineering constructs have been developed to block the contraction and scar formation mechanisms of repair and induce regeneration following injury.
Various therapeutic approaches including monoclonal antibodies (mAbs) have been developed to block Her2 activity to combat tumor growth (Keler et al. 1997; Ben-Kasus et al. 2009; Vasconcellos et al. 2013).
Recently, a variety of tissue-engineering constructs have been developed to block the contraction and scar formation mechanisms of repair, and to induce regeneration following injury with similar mechanisms of action observed for both the skin and peripheral nervous system (PNS).
Similar(44)
But drugs might be developed to block insulin receptor sites the way tamoxifen blocks receptor sites for the hormone estrogen.
The compound is being developed to block a type of enzyme that allows cancer cells to divide and spread and normal cells to be turned into cancer cells, a Vertex spokesman, Michael Partridge, said.
Therapeutics are being developed to block TGF-β signaling.
Professor Cullen believes a drug could be developed to block the microRNA whose job it is to suppress HSV-1 into latency.
Recently, certain chemokine receptor antagonists derived from chemokine peptides and small molecules were developed to block chemokine receptors [45].
More suggestions(15)
been developed to grow
been developed to manufacture
been developed to record
been shown to block
been used to block
been developed to improve
been developed to fight
been developed to target
been developed to transform
been ordered to block
been told to block
been developed to lower
been developed to address
been developed to do
been filed to block
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