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Although the effects of locally applied corticosteroids have not been determined, it has been suggested that this treatment may suppress the afferent ectopic firings at the site of nerve injury by an action of C fibers (nociceptive), reducing the release of neuropeptides [10].
Although the pathogenicity of RD-114 has not been determined, it has potential risks in that interspecies transmission may induce unpredictable diseases.
Although the properties and targets of SENP7 have not yet been determined, it has been established that SENP8 is an NEDD8-, rathan than SUMO-, sproteaseprotease (Hay, 2007).
While the three-dimensional structures of the isolated Btk domains have previously been determined, it has not been clear how these domains interact with each other and how they regulate the kinase domain.
Although the molecular mechanism of the antimycobacterial activity has not yet been determined, it has been proposed that UA and OA can produce significant abnormalities in the bacterial cell wall [ 9, 13].
Although, pharmacokinetics of Triphala in humans has not been determined, it has been used safely for centuries in the Ayuervedic medicinal system in India for the treatment of various gastrointestinal-related disorders.
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Although the source of ORFans genes in different genomes remains to be determined, it has been suggested that many of them are derived from bacteriophages [ 47, 52].
The leucine zipper allows FoxP proteins to form homo- and hetero-dimers [ 59, 60] and although the zinc finger function has yet to be determined, it has been suggested that it aids in dimer formation [ 60].
While the exact role of autophagy in asthma remains to be determined, it has been hypothesized that autophagy is likely an important modulator of the lack of viral-induced apoptosis noted in subjects with asthma [ 46].
While the underlying mechanism for the chromatin remodeling remains to be determined, it has been shown that liganded TR recruits chromatin remodeling complexes containing Brg1 and BAF57 to the TRE of the reporter gene [ 55, 78].
Although the exact incidence of peritoneal contamination with these procedures has yet to be determined, it has become evident that iatrogenic gastrotomy leads to seeding of bacteria in animal models [ 7, 8] and in humans as well [ 9].
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CEO of Professional Science Editing for Scientists @ prosciediting.com