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Further preexisting drug-resistance mutations have been detected in single, K65 wild-type, separate clones: K70R, V106A, and V108I.
Benzoaxinoids have also been detected in single isolated species of two distant related orders of dicots, the Ranunculales and the Lamiales [ 6].
However, the pathogenicity of many of the LRRK2 variants is unclear because they have been detected in single patients or also in patients and controls.
The selection criteria were based on the fact that these variants have been detected in single patients or also in patients and controls, and there have been no functional studies previously reported on these variants; hence, their pathogenicity is unclear.
Notably, dysregulation of the phosphatidylinositide 3-kinases (PI3K /AKT pathway by PI3K-mutations or aberrations that cause loss of the phosphatase and tensin homolog (PTEN) function, or mutations of BRAF, KRAS, or HRAS that activate the RAS/RAF/MEK pathway, have been detected in single cases, but their overall role in drug resistance is unclear [ 34, 35].
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Detection at the 2-Mb level identified 7 of the 10 mosaic events that had been detected in single-sample analysis by MAD.
Signatures of two other proteins, cystatin C and insulin-like growth factor-binding protein III, were detected in single samples, and in only a few cases did detection occur in all three technical runs.
(15 N2 incorporation was not observed in single DSS cells, but was detected in single DSB cells.
By using a random primed RT-PCR amplification strategy of grapevine double stranded RNA-enriched samples, viral agents were detected in single and mixed infections.
We also show that 10 nm-sized gold particles and quantum dot particles with 7 nm-sized cores can be detected in single cross-sectional images.
In the polarization analyses, we approximate the NBE emission as originating solely from the X A bound and free excitons and we neglect the effect of phonon replicas, which are one order of magnitude weaker than the main peak and which could not be detected in single nanowire spectra.
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