Sentence examples for been designed to bind from inspiring English sources

The agreement had been designed to bind investors in a common purpose, eliminating suspicion that they might betray one another.

One of the probes has been designed to bind to the silica backbone, while the other has been designed to bind to the transition metal species.

Small molecule probes of biological systems have traditionally been designed to bind to and inhibit the active sites of their protein targets.

SG1 has been designed to bind at the amyloid-β self-recognition site and prevent amyloid-β from misfolding into β sheet.

Despite the myriad of inhibitors, none to date have been designed to bind specifically to just one of the four mammalian Hsp90 paralogs, which are cytoplasmic Hsp90α and β, endoplasmic reticulum GRP94, and mitochondrial Trap-1.

O-Phenyl phosphonamidates have been designed to bind covalently by nucleophilic substitution to the serine residue in the active site of serine proteases, similarly to the diphenyl phosphonates used as standard.

In our efforts to abrogate DDX3 functions in vivo, we synthesized a small molecule inhibitor, RK-33, which was designed to bind to the nucleotide-binding site within the DDX3 protein and abrogate its functionality.

Most of the low molecular weight ADAM inhibitors use hydroxamate as the zinc binding group and were designed to bind to the MMP-like catalytic site [ 66- 69].

Similarly, natural nonheme proteins can also be designed to bind heme in a manner consistent with the cytochrome binding motif.

For example, enzymes can be fused to zinc fingers or other programmable DNA-binding domains and RNA aptamers can be designed to bind enzymatic partners.

These observations suggest that the amine binding pocket of Ch-MAL (and Ct-MAL) is designed to bind small amine compounds and excludes large nucleophiles.