To treat complex malignant tumors effectively, multifunctional nanomedicines with targeting ability, imaging properties and controlled drug release behavior should be designed and exploited.
A 'switching-on' fluorescent chemosensor for the selective and sensitive signaling of intraceullar Cr3+ has been designed and synthesized exploiting the guest-induced prohibition of the photoinduced electron transfer process between naphthyridine moiety and 7,10-diphenylfluoranthene moiety, the system shows a Cr3+-selective chelation-enhanced fluorescence response not only in ethanol but in cell.
A compound parabolic trough reactor has been designed and engineered to exploit both UV and visible part of the solar irradiation.
Moreover, dedicated data acquisition system has been designed and developed in order to fully exploit the detection rate performance of the detector.
Based on these results, a simulated moving bed (SMB) chromatographic process was designed and realised, which exploits a two-step salt gradient and allows the continuous separation of streptokinase from contaminants present in a clarified Escherichia coli cell lysate solution.
Major recent advances: Amphiphilic peptides, in other words, peptides that contain hydrophobic and hydrophilic regions along their lengths, have been molecularly designed and exploited in various ways.
Differential current conveyor II (DCCII) is designed, modified, and exploited as a comparator with reduced propagation delay and power consumption.
From the start it has been designed to exploit parallel and distributed computers to reduce simulation run times to manageable levels, without the additional modelling effort required for earlier publicly-available parallel simulation tools.
Dynamic model partition and adaptation-based load balancing solutions have been designed by exploiting common assumptions and model characteristics, in a user-transparent way.
Although NLO chromophores have been designed to exploit both dipolar and octupolar symmetry, the former has exhibited the strongest potential for the development of practical NLO devices.
