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Although the dual function of RIPK1 is best understood in the context of TNFα signaling, a wide range of other triggers, such as IFNαR, TLRs, viral infection, and genotoxic stress have recently been described to trigger RIPK1 activation and necrosome formation13.
Various stress conditions have also been described to trigger the expression of virulence factors [ 21].
Recently, 22 nt miRNAs have been described to trigger siRNA biogenesis from target transcripts in Arabidopsis [ 50, 51].
Triethyl amine (NEt3) has already been described to trigger polymerization of HA at 0 °C (Arslan et al. 2004).
EGFR activation has been described to trigger processes such as proliferation, apoptosis, migration, angiogenesis and differentiation [ 44– 44].
Downstream effects of C5a include upregulation of IL-8 [ 7] and other proinflammatory mediators, which have been described to trigger catabolic metabolism of cartilage.
Similar(49)
In addition, expression of an activated form of Akt was described to trigger spontaneous adipocyte differentiation of 3T3-L1 preadipose cells [55], [56], in support of a role of Akt in regulating PPARγ in fat cells.
In addition, nutrient deprivation was described to trigger lysosomal proteolysis of I κB α through its binding to heat shock protein 73 (hsc73) and lysosomal glycoprotein 96 (Igp96), a lysosomal membrane receptor.
We added febrile convulsion, as it has been described to be triggered by influenza infection in children [17] and acute respiratory distress, which at the start of the pandemic was highlighted as a clinical presentation among severe cases with the novel influenza [18].
Snail is a highly unstable protein, with a half-life of about 25 min, and its degradation has been described to be triggered by glycogen synthase kinase 3 β phosphorylation and mediated by the ubiquitin proteasome system (UPS).
As effectors, cytotoxin-associated gene A (CagA) and peptidoglycan have been described to alter and/or trigger host cell signaling.
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been considered to trigger
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