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Importantly CD4+ T cells have also been described to develop cytotoxicity and they are able to eradicate established melanomas [ 39].
Interestingly, mice lacking PPARα have been described to develop cardiac dysfunction due to oxidative stress ([40], path 2).
Acute GVHD (aGVHD) has classically been described to develop within 100 days after HSCT, but can sometimes occur at later time points.
Immunosuppressed patients with malignancies, organ transplants, and cytotoxic treatments for various reasons are the other large, though extremely heterogeneous, group of patients that have been described to develop HSV-1 pneumonitis.
We will use existing measures as a starting point in this process (wherever possible), and we will follow the standard procedures that have been described to develop measures of these theoretical constructs (e.g. [ 66]).
Aged Ccl2 −/− and Ccr2 −/− mice have also been described to develop the more discrete subretinal MP accumulation that occurs in older mice compared to Cx3cr1 deficient mice, associated with little to no photoreceptor degeneration (see Supporting Information data) (Chen et al, 2011; Luhmann et al, 2009).
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Since D3H2LN was described to develop bone and soft tissues metastasis after intracardiac injection in nude mice [15], we further studied the effect of both BPs on this D3H2LN metastasis model (Fig. 7).
Carpal malalignment following the malunited distal radial fracture is described to develop as an adaptation to realign the hand to the malunion.
Lipoxygenases (LOX1 and LOX2) enzymes, that catalyse the first committed step in JA biosynthesis, have been described to be expressed in developing embryos [ 44].
Of these patients, 55% have been previously described to develop muscle wasting defined by measuring a cross-sectional area of the rectus femoris by ultrasound.
Finally, MIDI library also contained a RIKEN cDNA 2310015N07 gene that was described to be isolated from developing mouse libraries but no function yet has been attributed [ 75].
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