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The background modeled by the null hypothesis has been described previously using either a Poisson [15], [32] or negative binomial model [28], [30] parameterized based on the coverage of low-density regions in the ChIP sample.
The existence of nontypeable H. pylori strains has been described previously, using similar primers [ 23].
The effect of cardiopulmonary bypass on factor concentration has been described previously using a prime of fresh whole blood.
A fluorescence-based assay for quantifying the DNA content of cells has been described previously using flow cytometry and the fluorescent DNA probe Picogreen.
Population fracture distributions have been described previously using administrative data, including x-ray reports, 1 4 and using survey data, 5 with widely varying results.
The reason for nonlinear kinetics in these samples is unknown, although this phenomenon has been described previously using ethanol as a substrate (Dalziel and Dickinson 1966).
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Such an approach has been described previously for transcriptomics using pooled RNA microarrays (e.g. [10]).
The use of CPAP as an RM has been described previously [ 26] using 40 cm H2O for all patients.
Transthoracic Doppler echocardiography, which has been described previously [ 14], was used to measure CFR.
Antibodies against mouse Sepp have been described previously [25] and were used at 1∶400 dilution.
Peptides used have been described previously.
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