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But the suspected knock-on effects on other species had not been demonstrated until now.
Oxidative stress and alterations in DNA methylation have also been observed in diabetes, but no clear correlation between these events has been demonstrated until now.
Recently, GilR was identified as the first bicovalently linked dehydrogenase, and for most pollen allergens, no catalytic function had been demonstrated until now.
However a functional impact of this part of the ubiquitin-proteasome system on either vascular cell proliferation or collateral growth has not been demonstrated until now.
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This dos not necessarily mean that they have a higher predictive value: with the exception of the above authors [ 8], a higher diagnostic value of these corrected moments could not be demonstrated until now [ 20].
The potential for trophic transfer of Pb in this form to predators is expected to be low, since metals in the form of MRG are generally supposed to be trophically unavailable, but this assumption is based on studies with other metals (Ag, Cd, Cu or Zn) and has not been demonstrated with Pb until now.
However, no biochemical activity related to PIG-A has been demonstrated from archaeal sources until now.
Human mitochondria contain four members of the release factor family, two of which (ICT1 and C12ofr65) are lacking the stop-codon recognition domains and are thought to be codon-independent hydrolases, an activity which has been demonstrated only for ICT1 until now.
Pigeons have now shown that they can learn abstract rules about numbers, an ability that until now had been demonstrated only in primates.
To our knowledge, their existence has not been demonstrated in the adult human brain until now.
Since aberrant activation of the Wnt pathway has been demonstrated to contribute to leukemogenesis and until now, in contrast to solid tumors, no activating mutations in the genes of the Wnt pathway have been described in myeloid or lymphatic malignancies, we investigated epigenetic regulation of SFRP-1, -2, -4, and - 5 as negative regulators of Wnt signaling.
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