Since toll-like receptors (TLRs), particularly TLR2 and TLR4, have been demonstrated to recognize endogenous ligands, including DAMPs, as well as microbial components [1], [3], [14], we examined TLR2 and TLR4 signaling for their involvement in the protection afforded by administration of rhBCL2 or rhBCL2A1.
Specifically, TLR2 and TLR4 recognize Gram-positive and Gram-negative bacterial cell wall products, respectively, while TLR5 recognizes a structural epitope of bacterial flagellin and TLR3, 7, 8 and 9 have been demonstrated to recognize different forms of microbial-derived nucleic acids [2], [13].
This antibody has been demonstrated to recognize a 46-kDa full-length WWOX protein.
Nam Pehchan's program has previously been demonstrated to recognize South Asian surnames with a sensitivity of 90-94% and positive predictive value of 63-96% [ 15].
Moreover, autoantibodies against gp210 have been demonstrated to recognize at least two different epitopes: one within the cytoplasmic tail and another located within the large glycosylated lumenal domain [ 17].
The polyclonal antiserum used in the ELISA has, however, been demonstrated to recognize both the glycosylated and non-glycosylated forms of cystatin E/M (data not shown), making this explanation less likely.
One of these capturable aptamers was demonstrated to recognize prion protein and change its conformation upon binding to it.
Following removal of the nitrite anion template, the europium [2]rotaxane host is demonstrated to recognize and sense fluoride selectively.
Serum samples from these 17 PTU-induced AAV patients in active stage, 12 PTU-induced AAV patients in remission, and 17 PTU-induced MPO-ANCA-positive patients but without clinical evidence of vasculitis were demonstrated to recognize all the six constructed linear protein fragments.
It has been demonstrated that recognizing emotions is not easy, even for humans, who employ specialized brain subsystems for the task [4].
