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Opioid receptors have been demonstrated to modulate various functions in the eye.
Through the galanin receptors GalR1-3, galanin has been demonstrated to modulate both glutamatergic and GABAergic neurotransmission, and this appears to be important in epilepsy and seizure activity.
TPR2 is a J-domain containing cochaperone which has been demonstrated to modulate GR and PR signalling [34], [35].
ROS have been demonstrated to modulate respiration in mammals by regulating several checkpoints energy pathways and mtDNA homeostasis.
Dopamine signaling via the D2 receptor (D2R) has been demonstrated to modulate the Akt-GSK3β pathway in vivo [29].
APC has also been demonstrated to modulate the host response to severe infection [ 9].
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Moreover, miR-217 was demonstrated to modulate epithelia cell senescence in metabolic disorders [ 13].
For instance, saturated fatty acids and different classes of polyunsaturated fatty acids (PUFAs) were demonstrated to modulate inflammation [13].
Acute and chronic morphine treatment was demonstrated to modulate Na+/K+ ATPase activity in the mouse hippocampus [ 50].
Shn3 was reported to decrease Runx2 protein stability in a ubiquitin-proteasome-dependent manner, whereas Twist2 and Maf were demonstrated to modulate Runx2 transcriptional activity.
The sex hormones in female and male rats respectively are 17ß-estradiol and testosterone which are demonstrated to modulate the HPA axis response to stressors.
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been demonstrated to express
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