Additionally, structural information, especially conservation of neighboring residues in 3D protein structures, has been demonstrated to be very useful in classifying catalytic residues [ 11, 12] and other functional sites [ 13, 14].
Indeed, miRNA profiling has been convincingly demonstrated to classify tumor and non-tumor samples more effectively than gene expression profiling and, more importantly, identifying breast cancer subtypes (Blenkiron et al. 2007; Iorio et al. 2005; Lu et al. 2005).
The proposed clustering method was demonstrated to be capable of classifying the soil into different levels of corrosivity severity.
Furthermore, it has been demonstrated that patients initially classified as "cold" CRPS showed more pain when re-evaluated several years after the initial assessment [3].
GPS's accuracy was demonstrated by classifying 83% worldwide individuals to their country of origin and 65% to a particular region of the country.
Finally, the effectiveness of this approach is demonstrated by classifying chemosensory and ABC transporter genes across all five sequenced Caenorhabditis species and some practical guidelines are given to users interested in comparative gene family classification.
Both these conditions remain to be demonstrated.
The ability to be demonstrated.
