Sentence examples for been demonstrated to activate from inspiring English sources

CD40 ligation has been demonstrated to activate ERK, and activation of ERK promotes cell survival.

Of interest, halothane has been demonstrated to activate VICC channel activity, while sevoflurane did not have any effect on these channels, in the rat aorta [ 9].

Interestingly, while etoposide has been demonstrated to activate ATM and ATR doxorubicin showed dose dependent activation of ATM and no ATR activation as determined by Ser428 phosphorylation.

In addition, immunoglobulin A in human milk with protease activity has been demonstrated to activate PAR-2 on intestinal epithelium, inducing hBD-2 expression via PAR-2 signaling [ 2].

Metformin, a common antidiabetic drug, improves insulin sensitivity and glucose homeostasis and has been demonstrated to activate AMPK in tissues from humans and rodents146,147.

This exposure to UVB has previously been demonstrated to activate JNK and subsequently increase phosphorylation of its substrate c-Jun [31].

In one study, metformin was demonstrated to activate AMPK and consequently decrease cellular proliferative activity, to produce a general decrease in protein synthesis in vitro in human breast carcinoma cells [ 30].

Gold nanoparticles coated with different functional peptide are demonstrated to activate or inhibit in vitro angiogenesis [32].

PFOS was demonstrated to activate the PI3K/Akt signaling pathway [ 39].

The Sp1/Sp3 cis-acting elements were demonstrated to activate the promoter of Axl in various cancer cell lines [ 41].

9-tricosene represents the first Drosophila cuticular hydrocarbon pheromone that, to our knowledge, is demonstrated to activate a Drosophila basiconic sensilla.