It has been demonstrated that the development of chlorotic leaves is related to chlorophyll metabolism and chloroplast development [ 5, 7, 9- 12].
It has been demonstrated that postnatal development of the hippocampus is affected by abnormal proliferation in the subgranule zone [47], [48], [52].
It has been demonstrated that for the development of a latent heat storage system (LHTS) in a building fabric, the choice of the PCM plays an important role in addition to heat transfer mechanism in the PCM.
It has been demonstrated that there is a development of woven bone surrounding the implants 1 week following placement in the rabbit tibia.
The neurodevelopmental actions of leptin are not restricted to the hypothalamus: it has been demonstrated that cortical and hippocampal development can also be influenced by leptin [53], [54].
It has been demonstrated that during early pancreas development, there are cells co-expressing Insulin, Glucagon, and Somatostatin spontaneously, which are multipotent islet precursors and can differentiate into all endocrine cell types [33], [34].
In addition, it has been demonstrated that the induction and development of experimental lupus is dependent on two stages of T cell activation and cytokine secretion: an early Th1-dominant stage represented by high IL-2 and IFN-γ expression followed later by a Th2-dominant stage represented by increased expression of IL-4 and IL-10 [ 50].
It has been demonstrated that IL-27 controls the development of Th17 and iTreg cells via differential effects on STAT1 [12].
Recently it also has been demonstrated that secreted SLIT3 guides vascular development by directing ROBO4-positive endothelial cell movements [ 50, 51].
It has been demonstrated that genetic background affects the development of PTEN-loss-induced tumors in mice (Freeman et al., 2006).
