This has similarities in AP response where while the exact mechanism has not been demonstrated, the response has been shown to be related to mechanical stimulation and also the cytoskeleton here.
Changes in iron metabolism have been demonstrated in response to acute S. Typhimurium infections in susceptible strains of mice [23] and in tissue culture macrophages [49].
Recently, p53-dependent repression of FAK has been demonstrated in response to estradiol in breast cancer cells [ 16].
However, a decrease in phosphodiesterase activity has never been demonstrated in response to an increase in PKA activity.
Modulation of an early posterior negativity has been demonstrated in response to various emotional stimuli including threatening images [ 44].
As discussed, significant changes in circulating RAAS components have been demonstrated in response to acute weight loss in humans [ 32].
A key role of AMPK in the mediation of eNOS phosphorylation has been demonstrated in response to hypoxia, metformin, adiponectin, and shear stress [9,14 17].
Tyrosine kinase activation is also related to melanogenesis, and it has been demonstrated that responses produced by its activation were attenuated by tyrosine kinase inhibitors [ 36].
It has recently been demonstrated that responses of TRAM-deficient mice to TLR2, TLR7, and TLR9 ligands are intact in terms of production of inflammatory cytokines [ 48].
An increase in nasal width has been demonstrated as a response to RME [1, 2, 19, 21].
