Sentence examples for been demonstrated previously with from inspiring English sources

Specific host association had been demonstrated previously with isolates from lineages I and II in cattle and lineage III in water buffaloes [ 14].

Inhibition of colony formation in such assays has been demonstrated previously with known tumour suppressors such as p53 (Crook et al, 1994).

Response: On this occasion, the purpose of the analysis is not to reinforce the relatedness of the RAMPs (which has been demonstrated previously with a variety of methods) but rather to provide a metric for comparison of different RAMP families.

Direct apposition between fibres and neurons has been demonstrated previously with confocal microscopy [ 29] while synaptic contacts between galanin-positive fibres and choline acetyltransferase (ChAT -positive neurons have been ChAT -positiveineuronsat using electron microscopy [ 33].

Also contributing to the increased [SID] in the NAA trial of the present study was a decreased plasma [Cl-], which has been demonstrated previously with oral NaHCO3 administration in horses [ 20, 21] and humans [ 2].

The validity of questionnaires asking about parental smoking and smoking in the home to determine pediatric exposure to SHS has been demonstrated previously, with questionnaire-determined SHS exposure confirmed by cotinine analysis [ 1, 34, 35].

A specific connection between p53 and phospholipid metabolism was demonstrated previously with indication of feedback regulation between phospholipid turnover and p53 activity [ 52- 55].

The efficacy of injecting immune stimulators in the vicinity of the lymph nodes for the treatment of cancer has been demonstrated previously; vaccination with tumour cell DC hybrids in the lymph node region led to regression of human metastatic renal cell carcinoma (Kugler et al, 2000).

Furthermore, tyrosine phosphorylation of ERBB2, ERBB3, VEGFR2/KDR, FGFR3, and FGFR4 has been demonstrated previously upon stimulation with conditioned medium supplemented with FGF-2 [36].

Increased production of superoxide from xanthine oxidase has been demonstrated previously in humans with coronary artery disease [1,30] whilst treatment with allopurinol has been reported to normalise endothelial function in diabetic subjects [31].

The success of the principle of combining DCA with a mitochondrial inhibitor in breast cancer cells has been demonstrated previously in vitro with the clinical agent arsenic trioxide, which was shown to inhibit complex IV of the ETC.