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Isolated anterior segment ischemia without inflammation has also been demonstrated in type II cryoglobulinemia [2].
This is supported by studies of growth in juvenile A. millepora in which increased skeletal growth has been demonstrated in type C1 compared to type D symbionts [13], [14].
A relationship between the changes in incretin secretion and β-cell function after lifestyle intervention has never before been demonstrated in type 2 diabetes.
Islet reactive T cells and autoantibodies have been demonstrated in type 1 diabetes, whereas islet autoimmunity in type 2 diabetes has been limited to islet autoantibodies.
EBV replication has been demonstrated in type II alveolar epithelial cells, and EBV latent membrane protein 1 (LMP-1) expression was detected in the alveolar epithelium in IPF patients, findings that were associated with poor prognosis [ 77].
The benefits of SMBG have been demonstrated in type 1 diabetes (T1DM) and insulin-treated type 2 diabetes (T2DM) [ 1, 2, 23]; however, findings from studies in non-insulin-treated T2DM have been inconsistent.
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The first experimental evidence of an adaptive immune function of the system was demonstrated in type II-A in Streptococcus thermophilus (Barrangou et al, 2007).
Also, progressive worsening of the endothelium-dependent vasodilator capacity of the myocardium with increasing insulin-resistance was demonstrated in type 2 diabetic patients [ 8].
This is the first time that the usefulness of an epigenetic cancer risk marker has been demonstrated in any type of cancer by a multicentre prospective cohort study.
It has been demonstrated in bovine type II collagen-treated mice that the TNFα expression peaks between day 21 and day 28 of the inflammation, which is then followed by a considerable decline by day 42 [ 43].
Conserved mechanisms across organ development/homeostasis and tumorigenesis have been demonstrated in many types of human cancers [47].
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