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The safety and efficacy of carotid endarterectomy (CEA) have been demonstrated in randomized trials, but these studies excluded patients thought to be at higher risk for poor outcomes.
While this has been demonstrated in randomized controlled trials, there is a need to confirm these findings in an everyday clinical setting.
The safety of these biologic therapies has been demonstrated in randomized clinical trials with no "off-target" angiogenesis, growth of occult tumors, or progression of diabetic retinopathy.
Although the efficacy and effectiveness of lifestyle modifications and antihypertensive pharmaceutical treatment for the prevention and control of hypertension and concomitant cardiovascular disease have been demonstrated in randomized controlled trials, this scientific knowledge has not been fully applied in the general population, especially in low-income communities.
The same is true also for riluzole, the efficacy of which has been demonstrated in randomized controlled trials [ 8, 9].
9 The efficacy and safety of desmopressin in the treatment of adults with nocturia have been demonstrated in randomized trials.
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That 100%% N2O for the pneumoperitoneum causes less pain after surgery than 100%% CO2, was demonstrated in randomized controlled trials [15, 16].
Equally, it could be argued that the benefits of risk prediction models in reducing pneumonia morbidity and mortality need to be demonstrated in randomized controlled trials.
The efficacy of infliximab, etanercept, adalimumab, and anakinra was demonstrated in randomized controlled trials in the majority of RA patients enrolled [ 1- 5]; however, less is known regarding the effectiveness of these drugs in daily rheumatological care.
Effectiveness of BT has been demonstrated in several randomized clinical trials.
The equivalence of olanzapine and amisulpride with regard to positive and negative symptoms has also been demonstrated in another randomized comparison study with 377 acutely psychotic schizophrenic patients, where 2 months after treatment onset no differences in BPRS total or BPRS factor scores, or depressive symptoms (Martin et al, 2002) were evident.
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been demonstrated in small
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been tested in randomized
been demonstrated in virtual
been demonstrated in human
been evaluated in randomized
been demonstrated in other
been reported in randomized
been demonstrated in prior
been conducted in randomized
been demonstrated in rigorous
been demonstrated in comparative
been demonstrated in clinical
been established in randomized
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com