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A gene referred to as Deadpan (Dpn) that encodes a bHLH transcription factor is another direct target of the Notch signaling pathway; so far this has only been demonstrated in intermediate progenitor cells [ 20].
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Immunocytochemical approaches also demonstrated S100β in damaged skeletal muscle [ 20] and adipose tissue [ 21], and S100β protein has also been demonstrated in villous and intermediate trophoblast cells of the normal human placenta [ 22- 24].
Increased ACE expression in intermediate monocytes has also been demonstrated in patients with abdominal aortic aneurysm and appeared to be independent of CKD classification [97].
As suggested by Figure 2, the preferred aggregation mechanism of HTT exon1-like peptides involves the initial formation of oligomeric intermediates, which have been demonstrated in vitro from incubation of both recombinant full-length HTT exon1 and chemically synthesized versions lacking full-length PRDs.
The involvement of benzynelike intermediates, called arynes, has been demonstrated in numerous reactions of aryl halides with strong bases.
The applicability of stacks with an external manifold structure can be demonstrated in planar intermediate temperature SOFC.
Combining LCM, in-situ SBM, and AQAMA assay, LINE-1 hypomethylation was demonstrated in low to intermediate grade adenoma, an early stage of colorectal tumorigenesis as previously shown [5], [6].
These comparatively longer branches are demonstrated in the network, and the intermediate characteristics of a third histamine-binding GPCR, labeled (a) in Fig. 2, are captured both in the tree and the network.
The obtained analyzed data allowed the qualitative and quantitative identification of these intermediates is demonstrated in scheme a, b in Fig. 9. Therefore, Fig. 10shows the variation of intermediates concentration formed during TCP degradation on sol gel ZnO films.
Since the efficacy of adjuvant radiation for patients with intermediate-risk factors were demonstrated in the previous trials [ 5, 9, 11, 12], radiation is the standard adjuvant therapy in patients with intermediate-risk factors.
This is demonstrated in figure 3B.
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