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Elevated DNA adducts, sister-chromatid exchange and somatic genetic mutation have been demonstrated in carriers of null GSTM1 and GSTT1 genotypes (Rebbeck, 1997).
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30 Uncinate fasciculus pathology has also been demonstrated in presymptomatic MAPT mutation carriers.
Increased body mass index (BMI), a broadly used index of obesity, has been demonstrated in Japanese Arg allele carriers [ 17].
Alterations in white matter structure have also been demonstrated in presymptomatic and early symptomatic carriers, with decreased fractional anisotropy in the fornix and widespread areas of brain visualized with diffusion tensor imaging [ 43].
In addition, another new NIR imaging approach to visualize sentinel lymph nodes has been demonstrated in animal studies using nano-carriers, such as quantum dots [31, 33 35] and dendrimers [36 38].
Moreover, transmission by immunocompetent carriers to susceptible hosts has been demonstrated in the mouse model (38 ).
HIV adherence to erythrocytes has been demonstrated in vitro, and it has been suggested that erythrocytes may be carriers of the virus.
A novel regulation of the physiologically/pharmacologically important human reduced folate carrier was demonstrated in response to increasing extracellular folates, involving: (i) increased transcripts and total protein, reflecting increased transcript stabilities; and (ii) increased endoplasmic reticulum trapping, due to impaired intracellular trafficking.
Compared to our study, both Kühn and van de Belt used larger sized samples, which may have influenced the total release[ 14, 15] The importance of carrier size was demonstrated in vivo by Walenkamp; small PMMA-beads established a markedly higher gentamicin release (over 90%) than larger ones.
This is demonstrated in figure 3B.
Many will be demonstrating in the streets.
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