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When bioconjugated with antibodies, the gold nanocages have also been demonstrated for specific targeting of breast cancer cells.
The symbiotic interactions between different bacterial species and the advantages associated with the biofilm phenotype have been demonstrated for specific aerobes and anaerobes.
Alternatively, sympathetic outflow to various adipose depots could differ, as has been demonstrated for specific WAT pads during prolonged fasting and following leptin administration [ 64, 65].
Suboptimal care for mental health problems has been demonstrated for specific psychiatric disorders (e.g., depression [ 3]) and for specific populations including women and individuals in low-income households or neighbourhoods [ 3- 6].
Whereas genetic redundancy, differential regulation of gene transcription, and alternative RNA splicing to produce protein variants have each been implicated as fundamental means by which evolution has tinkered with morphology, less importance has been demonstrated for specific amino acid (AA) substitutions in coding regions [ 1- 5].
Additionally, because acupuncture is a safe procedure and because there is no current treatment for which clinical efficacy has been demonstrated for specific tinnitus symptoms, acupuncture is an option for the treatment of tinnitus symptoms in patients who request this procedure in the clinic.
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Taken together, these data suggest that benefits can be demonstrated for specific applications and domains.
The dynamic range of the expression changes is expected to be muted by the normalization procedure, and this is demonstrated for specific transcripts below.
The benefit of a concept in which different processes are carried out in separate segments of the same reactor has been demonstrated for the specific case of biomass gasification.
Efficacy superiority has not been demonstrated for either a specific strategy or anti-viral drug in numerous clinical trials and meta-analyses [2] [4].
Targeted correction of the disease-causing mutations by homologous recombination in iPSC is well within reach and has been demonstrated for various disease-specific iPSC (Nakayama, 2010; Zou et al, 2011).
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