Several surfactants, such as sodium dodecyl sulfate (SDS) [15, 16], sodium dodecylbenzene sulfonate (SDBS) [16 19], and sodium cholate (SC) [20], have been demonstrated to efficiently disperse bundled nanotubes into aqueous suspensions of individual nanotubes.
However, none of these novel systems has been demonstrated to efficiently perform multi-dimensional range queries incorporating many boolean operators, a task which is commonly used in scientific data exploration, data warehousing and business analytics.
Lymphoid-resident DCs expressing a homodimer of CD8α have previously been demonstrated to efficiently cross-present soluble and cell-associated antigens [5], [6], [7], [8].
Whilst VEGF blockade has been demonstrated to efficiently reduce neovascularization progression and leakage in age-related macular degeneration, its exact place in the management of DR remains to be clarified.
Multiple in vitro stimuli have previously been demonstrated to efficiently synchronise cultured cells [ 32].
The perturbation of folate-mediated one-carbon metabolism by the multi-targeted antifolate pemetrexed has been demonstrated to efficiently activate AMPKα at Thr172; this process subsequently inhibits the mammalian target of rapamycin (mTOR) and the hypo-phosphorylation of the downstream targets of mTOR that control the initiation of protein synthesis and cell growth [ 49, 74].
A number of these have been demonstrated to be efficiently recombined by IntI1 [for a functional and structural analysis of the site see ref 6 and 7].
The CRISPR-Cas system has been demonstrated to work efficiently for genome editing in bacterial, yeast, and animal systems (Cong et al. 2013; DiCarlo et al. 2013; Gasiunas et al. 2012; Jinek et al. 2013; Mali et al. 2013) and has been applied to plants recently (Li et al. 2013; Nekrasov et al. 2013; Shan et al. 2013).
Pretreated WS has been demonstrated to be hydrolyzed efficiently even with low enzyme dosage [ 6, 28, 29].
In the preclinical mouse model of MM, it has been demonstrated that delanzomib can efficiently induce an improved response against bortezomib-resistant cells [ 106].
