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The complexity of aberrant gene interactions associated with metastasis has been demonstrated by multiple studies.
Significantly, the importance of identifying rare point mutations in ASD has been demonstrated by multiple studies.
The connection between cadherin-catenin proteins and the Hippo pathway components has been demonstrated by multiple studies and we will discuss these findings in more detail (see below).
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Consistency, accuracy and efficiency of the new boundary conditions are demonstrated by multiple numerical examples involving periodic symmetry and axisymmetry.
Using both species richness and Shannon's species diversity as descriptors, it was demonstrated by multiple regression analysis that ant return was positively associated with plant species richness and diversity, time since rehabilitation, percentage plant cover in certain strata, percentage litter cover, and the presence of coarse woody debris.
The nephrotoxicity of high molecular weight and high substitution rate HES administered at high posology in patients with severe sepsis and septic shock is demonstrated by multiple studies.
The importance of the circadian clock for human physiology is demonstrated by multiple reports that link disturbances in circadian oscillations to different pathologies in humans [ 4, 6].
In macrophages, the involvement of ACAT1 in foam cell formation has been demonstrated by studies, and multiple molecular mechanisms have been put forward.
For example, in the context of screening antibiotic toxicity, microdroplet based systems have already been demonstrated by carrying out multiple functional assays with minute samples (e.g., <100 μL).
The interactions between PGRN and TNFR have been demonstrated by many laboratories in multiple disease contexts, indicating that the balance of TNF-α/PGRN is crucial to the development of these diseases.
Albeit with varying degree of sensitivity and specificity, the properties of diffusely reflected light in discriminating a variety of oral lesions have been demonstrated by our group in multiple studies using point monitoring systems.
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