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Interestingly for tiparp a xenopbiotic response element has been defined in mouse in the first half of intron 1 [ 82 ].
Comparable stem cell subsets have been defined in mouse mammary tumors, which share many conserved genes with their human counterparts [ 92].
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The pathway of renin secretion has been defined in the mouse submandibular gland (SMG).
Susceptibility loci for colitis in particular have been defined in the mouse, although specific candidate genes have not been identified to date.
Three broad categories of defects that can lead to a lupus-like phenotype have thus been defined in the mouse and are instructive for thinking about B-cell abnormalities in human SLE.
Over 20 MCMV-derived CD8 epitopes have been defined in C57BL/6 mice [32].
The number of lncRNAs we identify in An. gambiae is more than double the number identified in D. melanogaster and other members of the genus Drosophila, for which more than 1,000 long intergenic non-coding RNAs (lincRNAs) have been identified in each species, and many fewer than have been defined in studies of mice and humans, which have identified many thousands of potential lncRNAs [ 44, 45].
The latter group now consists mostly of cobblestone malformations, although less severe forms of these have been defined in foetal alcohol syndrome and in mice with mutations of some transcription factors such as Foxc1 (Zarbalis et al., 2007).
The three compositionally different regions were defined in the complete mouse promoter sequence dataset.
Instruction about basic principles of genetics is minimal, with a 'knock-out' mouse being defined in terms of a transgenic mouse, for readers who know what the latter is.
Using Image J software (National Institutes of Health), regions of interests (ROI) were defined in all consecutive slices of one mouse.
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