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Members of HER family take part in a complex array of combinatorial interactions through the formation of homo and heterodimers between the different family members and not only the preferred heterodimerization partner HER2, but also EGFR and recently HER3 have been defined as important therapeutic targets in breast cancer [6].
An improvement of a little or somewhat better has been defined as important [ 23].
Questionnaire development and evaluation followed criteria that have been defined as important in patient satisfaction measurement [ 23].
Most of these amino acids have been defined as important amino acids in the literature; thus, this hydrophobic interaction analysis is credible to present the selected compounds effect on CXCR4.
Diverse external factors, such as hypoxia (hif-1-pathway) and the activation of adenosine receptors, as well as internal cellular alterations like the inactivation of tumour-suppressor genes pVHL, p53 or the overexpression of NFkB have been defined as important molecular regulators of the CXCR4 expression (Helbig et al, 2003; Staller et al, 2003; Mehata et al, 2004).
Similar(55)
"What kind of issues will be defined as important or not?" he asked.
Such bridges are defined as "important" by ATC-18 (1997), which stipulates that full access to "important" bridges should be possible within three days after an earthquake.
Strategic choices can be defined as important, infrequent decisions made by a firm's upper echelon that tie up resources and may critically affect the company's future (Eisenhardt and Zbaracki 1992; Mintzberg et al. 1976).
A theme is an expression or context being defined as important by the researchers.
Lesions consistent with occult bleeding were defined as important, and were classified into three major categories, as follows in flow diagrams: neoplastic, inflammatory and vascular.
For this study, quite a lot and very much were defined as "important" motives (a lot), and not at all and slightly as "not important" motives (hardly at all).
More suggestions(18)
been described as important
been defined as crucial
been defined as major
been outlined as important
been determined as important
been characterised as important
been designated as important
been recognized as important
been used as important
been considered as important
been reported as important
been argued as important
been defined as attentive
been defined as proteinaceous
been defined as random
been proposed as important
been implicated as important
been recognised as important
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com